All-biological BioIntegral Surgical Bifurcated Vascular Graft

All-biological BioIntegral Surgical Bifurcated Vascular Graft

A Totally Biological Perima™ and Perima™ Bifurcation

The only biological graft that compares well with the autogenous

• Clinical experience with over 400 patients and 9000 BioConduit implants, prove resistance to infection at least as good as the autogenous vein1,2,3
• Overwhelming results show resistance to stenosis, calcification, dilatation, and thrombosis
• Made from bovine pericardium for superior strength
• Substitute for replacing vascular bifurcated grafts or tissue in patients with infection or at high risk of infection
• Saves 3 to 4 hours in tailoring the autogenous bifurca-tion (see complete clinical manual)

The BioIntegral Surgical Technology

The BioIntegral Surgical biomodified technology functions to allow growth of the endothelium on all blood contacting surfaces.
• Reduced toxicity
• Enhanced biocompatibility
• Lower rates of infections, adhesions and calcifications4
• Allows for endothelialization, thus enhances patency better than any other vascular graft3,5,8

 

 

References
1. Amir Aboholda, et al., “No-React Detoxification Process: A Superior Anticalcification Method for Bioprostheses.” Ann. Thor. Surg. 62 (1996) 1724-30.
2. Michele Musci, et al. “Surgical therapy in patients with active infective endocarditis: sev- en-year single centre experience in a subgroup of 255 patients treated with the
Shelhigh stentless bioprosthesis,” Eur. J. Card. Surg. 34 (2008) 410-417.
3. Michele Musci, et al. “Further Experience with the “No-React” Bioprosthesis in Patients with Active Infective Endocarditis: 11-Year Single Center Results in 402 Patients”
Eur. J. Card. Surg. 61 (2013) 398-408.
4. Yerebakan, C., et al., “Long-term results of biventricular repair after initial Giessen hy- brid approach for hypoplastic left heart variants,” J. Thor. Card. Surg. 149 (2015).
5. Meduoye, A., Sosnowski, A. and Manuel Galiñanes, “No-React Composite Stentless Aortic Valved Conduit: A Decade of Experience,” Presented at Ten Years Follow-Up
with No-React Heart Valves, Toronto, Canada. (May 2nd, 2010).
6. Proal, A. “Understanding Biofilms,” Bacteriality (2008).
7. Leid, J.G., “Bacterial Biofilms Resist Key Host Defenses,” Am. Soc. Microbio., (2009).
8. Victor O. Morell and Peter A Wearden, Experience With Bovine Pericardium for the Re- construction of the Aortic Arch in Patients Undergoing the Norwood Procedure,“
Ann. Thor. Surg. 84 (2007) 1312-1315. (Article of Interest)

BioIntegral Brochure

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