Your Treatment. Reimagined.

Precision Empowered.

The NanoKnife System gives a physician the ability to sculpt and control the ablation zone through a variety of electrode configurations.¹

IRE effectively destroys the targeted tissue and gives you precise treatment margins resulting in confident treatment coverage for your procedure.^4,5

Preservation Redefined

The procedure spares vital structures by retaining the structural integrity of the targeted tissue.^2,3

The delivery of non-thermal energy allows for the preservation of the extra-cellular matrix, facilitating post-ablation, histological and functional tissue regeneration.^2,3

Versatility Perfected.

Multiple electrode configurations, coupled with a unique mechanism of action, allow the device to be used in all segments of an organ to optimize treatment delivery.2

Electrodes can be confidently placed near vital structures, maximizing your ability to personalize treatment to your patient’s anatomy. 4,5

The Nanoknife 3.0 System

References

^{1 Blazevski A, Amin A, Scheltema MJ, Balakrishnan A, Haynes AM, Barreto D, Cusick T, Thompson J, Stricker PD. Focal ablation of apical prostate cancer lesions with irreversible electroporation (IRE). World J Urol. 2020 Jun 2. doi: 10.1007/s00345-020-03275-z. Epub ahead of print. PMID: 32488359.}

^{2 Scheltema MJ, Chang JI, van den Bos W, Gielchinsky I, Nguyen TV, Reijke TM, Siriwardana AR, Böhm M, de la Rosette JJ, Stricker PD. Impact on genitourinary function and quality of life following focal irreversible electroporation of different prostate segments. Diagn Interv Radiol. 2018 Sep;24(5):268-275. doi: 10.5152/dir.2018.17374. PMID: 30211680; PMCID: PMC6135060.}

^{3 Li W, Fan Q, Ji Z, Qiu X, Li Z. The effects of irreversible electroporation (IRE) on nerves. PLoS One. 2011 Apr 14;6(4):e18831. doi: 10.1371/journal.pone.0018831. PMID: 21533143; PMCID: PMC3077412.}

^{4 Lee EW, Thai S, Kee ST. Irreversible electroporation: a novel image-guided cancer therapy. Gut Liver. (2010);4(SUPPL. 1):99–104. doi: 10.5009/gnl.2010.4.S1.S99}

^{5 Guidance for Selection of NanoKnife Probe Array Configuration and Ablation parameters for the Treatment of Stage III Pancreatic Cancer}

^{AngioDynamics, the AngioDynamics logo, NanoKnife, and the NanoKnife logo are trademarks and/or registered trademarks of AngioDynamics, Inc., an affiliate or a subsidiary. © 2021 AngioDynamics, Inc. GL/ON/WP/1053 Rev 01 07/21}