The Fluent platform is the complete automated solution for common laboratory applications including:

• Genomics
• Cell Biology
• Drug Discovery & Development
• Clinical Applications
• Applied Markets such as Agriculture, veterinary & Food/Beverage

System Options

Available in 3 sizes based on throughput needs:

• Fluent 480

• One or Two arms
• Compact workhorse ideal for small laboratories & single liquid handling workflows
• 1,150 x 785 mm
• Deck accommodates 30 SLAS-format microplates or disposable tip stacks, or up to 960 tubes, plus waste & reagent positions

Fluent 780

• Up to 3 arms
• Flexible, mid-size system for complete process automation
• 1,650 x 785 mm
• Deck accommodates 48 SLAS-format microplates or disposable tip stacks, or up to 1,600 tubes, plus waste & reagent positions

Fluent 1080

• Up to 3 arms
• High capacity system for complete process automation or high batch capacity liquid handling
• 2,150 x 785 mm
• Deck accommodates 72 SLAS-format microplates or disposable tip stacks, or up to 2,000 tubes, plus waste & reagent positions

Highlights

• Fast, streamlined performance
  • Up to 3 independent, task-specific arms
  • Combine pipetting, detection, separation 7 logistics steps in automated workflows
• Optimised walkaway times
  • Up to 6 microplates or tip boxes in the worktable
  • Stacked r nested tips allow an increased on-deck capacity
  • Multiple device integration on, around or below the deck
• Robotic Gripper Arm
  • Versatile tip, tube & plate handling
  • Smart interfacing between worktable & integrated devices
  • Works interdependently, without disrupting pipetting process
  • Finger Exchange System™ further extends labware format range and device that can be accommodated
• Reduced Footprint
  • Flexibility to increase capacity by utilising the space below the deck
• Measure & Improve Liquid Handling Efficiency
  • Cloud-based Introspect™ gives a comprehensive overview of how the automated systems are used
  • Real-time data on instrument uptime, consumable consumption & run success
• Ease of Use
  • Guided start-up & workflows
  • Touchscreen operator interface
  • Easy programming
  • Instant Stop & Resume function to access work-deck during runs
  • 3D simulations to test new assays without using reagents or consumables
• High performance pipetting:
  • Single & multiple tip formats, either disposable or washable tips
  • Flexible Channel Arm™ provides a choice of air- or liquid-displacement pipetting
  • Multiple Channel Arms offer 96and 384 channel formats in one head

System Modules

Flexible Channel Arm™

• 8 independent pipetting channels with automatic span adjustment (9 – 38mm)
• Choice of liquid or air-displacement
• Individual liquid detection, pipetting evaluation, error handling & piercing for each channel
• Air Flexible Channel Arm (Air FCA)
  • Air displacement pipetting from 500 nl
  • 10, 50, 200, 350 & 1000µl disposable tips
• Flexible Channel Arm (FCA)
  • Liquid displacement pipetting (200nl  >5ml)
  • Disposable or washable tips or a combination of both
• Adaptive Signal Technology™ for minimising dead volumes
• Dual FCA: offers 16 pipetting channel flexibility & speed, both arms working independently
• Flexible Channel Arm Gripper for complete process automation

Multiple Channel Arm 384/96

• 384 channel head for volumes from 250nl  125µl
• One arm for both 96 & 384 formats with automatic switching in seconds
• Ability to switch between disposable or fixed tips
• Compatible with 1,536 well plates
• Extended volume up to 500µl for 96 channel

Robotic Gripper Arm™

• Swift transfer of labware between pipetting area and devices for storage, detection & processing
• Access to peripheral devices below the deck & periphery
• Choice of different gripper fingers with 360 ͦ rotation
• Finger Exchange System gives the ability to change gripper fingers at any time
• Mountable barcode scanner for 1D codes

Dynamic Deck™

• 6 plate or 32 tubes capacity in the depth of the worktable
• Easily loadable & configurable for custom deck layouts
• Unique double deck supports modules below the worktable
• Easy & flexible integration of devices via Grid Adapters
  • Accommodate device feet securely while still allowing easy removal
  • Reposition devices as plans change without the cost of designing new adapter plates

Add-ons & Accessories

Barcode Scanning:

• 1D & 2D barcode scanning available for sample tubes & microplates
• FluentID™ allows loading & reading of 96 samples < 30 seconds
• Barcode scanner on the Robotic Gripper Arm™ scans microplate codes in situ on the deck or in hotels
• Fixed position barcode scanner reads both 1D and 2D barcodes on plates & tubes presented to it by the Robotic Gripper Arm™
• Fluent Stacker & Carousel have an optional built-in 1D barcode reader

Fluent Carousel:

• Can be located to the left or right of the deck
• Accommodates over 200 plates
• Optional built-in barcode scanner
• Pipetting directly to/from plates in the carousel
• Transfer to the deck via Robotic Gripper Arm™

Hotels:

• Available for disposable tips, 9 standard microplates or 5 deep-well plates
• Can be placed below the deck, in the side wall spaces or at the rear of the instrument

Heating & Cooling

• For on-deck during processing or incubation/acclimatised storage
• Six-slot MIO™
  • Suitable for standard microplates with/without lids
  • Ambient +5  53 ͦC (with shaking) or 63 ͦC (without shaking)
  • Electronic temperature logging & tracking
• Four-slot MIO™
  • Suitable for standard microplates with/without lids up to 35mm high
  • Ambient +5  53 ͦC (with shaking) or 63 ͦC (without shaking)
  • Electronic temperature logging & tracking
• Te-Shake™ robotic shaker with heating option from ambient +5  80 ͦC
• Heating/cooling deck segment for up to 4 microplates controlled by external circulating device
• Thermal cycling for genomic applications

Contamination Solutions

• Off-the-shelf & custom containment solutions available
• Delivery of clean air to maintain sterile environments
• Laminar flow, according to ISO class 5
• Manual door opening during a run facilitated by ramp-up protection
• Audible & visual warnings of potential environment compromises
• UVC light for between-process sterilisation
• Top cover prevents dust & debris falling onto the system

Detection Instruments:

• Incorporate Spark™, Infinite® 200 Pro series 7 third-party readers at the rear, sides or below the deck

Separation Technologies:

• Microplate washers
  • Hydrospeed™ washer for whole 96- & 384-well plate washing
  • HydroFlex™ washer for 8- or 16-channel strip washing
• Vacuum solid phase extraction
  • Te-VacS™ provides an automated vacuum extraction workflow for cartridge-based filtration & SPE
• Magnetic separation
  • Integrated commercial magnets for magnetic separation techniques
  • Free positioning of single or multiple magnets on standard deck positions
  • Fast transfer of plates between pipetting position & magnets
• Sample fractionation via Te-Chrome™
• Colony picking using the Picolo™ Colony-Picker for ID and picking of specific colonies of interest

Mixing & Shaking

• Te-Shake™ robotic shaker
  • Heating option from ambient +5  80 ͦC
  • Orbital, reverse orbital or amplitude shaking
• BioShake 3000 series
  • Mixing at up to 3,000 rpm for standard & deep-well plates
  • Up to 1,800 rpm for microfuge tubes
  • Electronic locking of plate during shaking
  • Heating option from ambient to 99 ͦC
• Turnable mixer
  • Automated mixing of 50ml conical tubes